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Blog: MenoPause ~ take time to think about it

Antidepressants and your bone health

by Margery Gass | Oct 21, 2013
There’s good news about your bones this week: Women in middle age do not need to worry about the bone effects of using antidepressants. No association between use of antidepressants and later changes in bone mineral density was found in a new study, analyzing 10 years of data from 1,972 women in the Study of Women’s Health Across the Nation. The women were ages 42 to 52 years at the beginning of the research period. Selective serotonin reuptake inhibitors and tricyclic antidepressants were the specific medications studied.


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  1. 1 Ricki Pollycove 27 Oct
    Depression has long been recognized as "a missing link" in understanding etiologies for osteoporosis and low bone density.  Patients who have appeared refractory to what should be  "complete treatment for osteoporosis," { adequate vitamin D, calcium intake from nutritional sources, food and supplements, life style factors: weight-bearing and resistance exercise, and prescription agents that favor anabolic bone building (estrogen, bisphosphonates, denosumab,  calcitonin agonists, etc)} more often are also diagnosed with depression.  The data from SWAN help to eliminate confounding contributions of depression as a factor from potential side effects of anti depressants themselves. Thanks for your comments, Margery.

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MenoPause: the blog!

Posts to our Blog are written by NAMS staff members and Dr. Margery Gass. All posts are reviewed and edited by Dr. Gass. We strive to bring you the most recent and interesting information about various aspect of menopause and midlife health. We accept no advertising for our website. We want you to have accurate, unbiased, evidence-based information. 

Margery L.S. Gass, MD, NCMP
NAMS Executive Director

An internationally recognized leader in the field of menopause, Dr. Gass became Executive Director of The North American Menopause Society in 2010. Dr. Gass has been an investigator on numerous research projects, including serving as a principal investigator for the Women’s Health Initiative, and has published and presented on a wide range of topics related to menopause, including osteoporosis, sexual dysfunction, and hormone therapy.

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