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Which hormones are better?

by Margery Gass | Sep 11, 2012
There’s been a lot of talk about how “bioidentical” hormones and transdermal hormones (in skin patches or gels) may be safer options than the oral pill hormones used in the Women’s Health Initiative Studies. There’s been some research, too, hinting that transdermal estradiol (a bioidentical hormone in FDA-approved forms such as patches, creams or gels) and micronized progesterone (also bioidentical and government approved) might cause fewer blood clots. But we won’t know for sure until we see results from large-scale randomized trials, which may not be done anytime soon. Do different formulations of hormone therapy have different effects on blood pressure, cholesterol levels, progression of atherosclerosis, memory, or quality of life? The Kronos Early Estrogen Prevention Study (KEEPS) will answer many of these questions. Stay tuned because the results are coming soon. In fact, the first results from the trial will be presented at the NAMS Annual Meeting in Orlando in October.

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1 Comment

  1. 1 Marcia 21 Sep
    From the age of 35 to 48 I complained to my doctors, both G.P. and Obgyn.  that my hair was starting to fall out, I was tired, didn't sleep well. had urgency issues and really was becoming less and less interested in sex, as well as gaining about 70 lbs. over ten years. Also had a brand new asthma condition as well as allergies I never had before. They did blood work, told me to take anti depressants, exercise more, see a lung spec. Finally when I showed up in my OB's office for my yearly and I was so tired I was near to hysterics(you try not sleeping at all for 3 days) he did more blood work. All of my levels were midline normal except for testosterone which was low but still in the normal range. He suggested implanting a testosterone pellet. This man has given me back my life. I have energy again, I can sleep. I want to have sex. My hair loss has slowed considerably. I don't want to eat all of the time and I'm not depressed. Also my allergies are abating. If only someone had heard me 13 years ago...we need not only estrogen to be normal but testosterone.  So why do only men get help with this before there's a crisis?



MenoPause: the blog!

Posts to our Blog are written by NAMS staff members and Dr. Margery Gass. All posts are reviewed and edited by Dr. Gass. We strive to bring you the most recent and interesting information about various aspect of menopause and midlife health. We accept no advertising for our website. We want you to have accurate, unbiased, evidence-based information. 

Margery L.S. Gass, MD, NCMP
NAMS Executive Director

An internationally recognized leader in the field of menopause, Dr. Gass became Executive Director of The North American Menopause Society in 2010. Dr. Gass has been an investigator on numerous research projects, including serving as a principal investigator for the Women’s Health Initiative, and has published and presented on a wide range of topics related to menopause, including osteoporosis, sexual dysfunction, and hormone therapy.


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